Role of amylase and lipase in diagnosis of acute pancreatitis

Lavanya Lagisetty, Radhika Chowdary D

Pdf Page Numbers :- 6-10

Lavanya Lagisetty^1,*, and Radhika Chowdary D¹

¹Department Laboratory Medicine, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003.Telangana, India

*Corresponding author: Dr. LavanyaLagisetty, MD (Biochemistry), Department Laboratory Medicine, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003.Telangana, India. Email: lavanyamacha99@gmail.com

Received 27 September 2017; Revised 24 November 2017; Accepted 05 December 2017; Published 16 December 2017

Citation: Lagisetty L, Chowdary RD. Role of amylase and lipase in diagnosis of acute pancreatitis. J Med Sci Res. 2018; 6(1):6-10. DOI: http://dx.doi.org/10.17727/JMSR.2018/6-2

Copyright: © 2018 Lagisetty L et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

The study is carried out to establish utility of single enzymatic marker for the diagnosis of acute pancreatitis (AP). This is a retrospective study and suspected cases of acute pancreatitis (n = 127) admitted in the hospital between January 2017 - December 2017 were included in the study. Serum amylase and lipase were performed along with many other analytes. All relevant data including serum lab values and imaging were collected. Out of 127 suspected cases, 110-patients had both amylase and lipase raised, 14 patients had amylase normal, lipase raised. One patient has lipase normal and amylase raised and two patients have both lipase and amylase normal. It was found that alcoholics were more in 41-60 years age group. The results show that among 127 studied patients, 100 (78.74%) were men and 27 (21.26 %) were women. Study shows that in patients with AP, amylase average was 1971.5 IU/L and lipase average was 2470 IU/L. In smaller hospitals, where limited lab and radiological facilities are available, estimation of serum lipase will be a better choice over serum amylase in diagnosis of acute pancreatitis.

Keywords: amylase; lipase; acute pancreatitis