Haemophilic arthropathy

Sarath Chandra Mouli V, Pradeep H

Pdf Page Numbers :- 225-227

Dr. V. Sarath Chandra Mouli^1,* and H. Pradeep¹

¹Department of Rheumatology, KIMS Hospitals, Secunderabad, Telangana, India

*Corresponding author: Dr. Sarath Chandra Mouli Veeravalli, MD (NIMS), MRCP (UK), Chief Rheumatologist, Department of Rheumatology, KIMS Hospitals, Secunderabad, Telangana, India. Email: chandramouli776@gmail.com

Received 14 July 2014; Revised 24 August 2014; Accepted 03 September 2014

Citation: Sarath Chandra Mouli V, Pradeep H. Haemophilic arthropathy. J Med Sci Res 2014; 2(4):225-227. DOI: http://dx.doi.org/10.17727/JMSR.2014/2-039  

Copyright: © 2014 Sarath Chandra Mouli V, et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PDF

Abstract

Acquired haemophilia (AH) is extremely rare and potentially fatal bleeding disorder and it is associated with significant morbidity and mortality rate between 7.9% to 22%. Upto 90% of people with AH experience bleeding. It is mainly due to the spontaneous development of auto antibodies that inhibit the coagulant activity of factor VIII (FVIII). Autoimmune disorders (16.6%) like Rheumatoid arthritis, Systemic lupus erythematosus (SLE), Multiple Sclerosis etc., may lead to trigger acquired inhibitors to Factor VIII. In the case report we described a 70-year-old male patient who has history of migratory joint pains and swellings for five months and on physical examination there was an echymotic rash over the left hand elbow and left groin extending into the left thigh and we reemphasize that even though a series of effective treatment options available, a through workup, early diagnosis and early treatment are important.

Keywords: Haemophilic arthropathy; Acquired Haemophilia; Rheumatoid arthritis